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  1. Review article

    The association between brain-derived neurotrophic factor gene polymorphism and migraine: a meta-analysis

    Migraine is a recurrent headache disease related to genetic variants. The brain-derived neurotrophic factor (BDNF) gene rs6265 (Val66Met) and rs2049046 polymorphism has been found to be associated with migrain...

    Xiaoying Cai, Xiaolei Shi, Ximeng Zhang, Aiwu Zhang, Minying Zheng and Yannan Fang

    The Journal of Headache and Pain 2017 18:13

    Published on: 2 February 2017

  2. Research article

    Volume gain of periaqueductal gray in medication-overuse headache

    Periaqueductal gray (PAG) is a substantial descending pain modulatory center, and previous voxel-based morphometry study confirmed the clusters with increased volume in PAG region in medication-overuse headach...

    Zhiye Chen, Xiaoyan Chen, Mengqi Liu, Shuangfeng Liu, Lin Ma and Shengyuan Yu

    The Journal of Headache and Pain 2017 18:12

    Published on: 1 February 2017

  3. Erratum

    The Journal of Headache and Pain 2017 18:11

    Published on: 31 January 2017

    The original article was published in The Journal of Headache and Pain 2015 16:A52

    The original article was published in The Journal of Headache and Pain 2015 16:A160

    The original article was published in The Journal of Headache and Pain 2015 16:A87

    The original article was published in The Journal of Headache and Pain 2015 16:A1

    The original article was published in The Journal of Headache and Pain 2015 16:A49

    The original article was published in The Journal of Headache and Pain 2015 16:A106

    The original article was published in The Journal of Headache and Pain 2015 16:A99

    The original article was published in The Journal of Headache and Pain 2015 16:A90

    The original article was published in The Journal of Headache and Pain 2015 16:A54

    The original article was published in The Journal of Headache and Pain 2015 16:A91

    The original article was published in The Journal of Headache and Pain 2015 16:A59

    The original article was published in The Journal of Headache and Pain 2015 16:A158

    The original article was published in The Journal of Headache and Pain 2015 16:A55

    The original article was published in The Journal of Headache and Pain 2015 16:A58

  4. Short report

    Endovascular thrombectomy and post-procedural headache

    We investigated the prevalence of post-procedural headache in patients who have undergone thrombectomy for ischemic stroke, and correlated history of migraine with risk of peri-procedural complications. A tota...

    Sabrina Khan, Faisal Mohammad Amin, Markus Holtmannspötter, Klaus Hansen, Anna Maria Florescu, Zainab Fakhril-Din, Julie Falkenberg Petersen, Hashmat Ghanizada, Cenk Ayata, David Gaist and Messoud Ashina

    The Journal of Headache and Pain 2017 18:10

    Published on: 28 January 2017

  5. Research article

    Simulated airplane headache: a proxy towards identification of underlying mechanisms

    Airplane Headache (AH) occurs during flights and often appears as an intense, short lasting headache during take-off or landing. Reports are limited on pathological mechanisms underlying the occurrence of this...

    Sebastian Bao Dinh Bui, Torben Petersen, Jeppe Nørgaard Poulsen and Parisa Gazerani

    The Journal of Headache and Pain 2017 18:9

    Published on: 28 January 2017

  6. Research article

    Interictal brain activity differs in migraine with and without aura: resting state fMRI study

    Migraine is one of the most severe primary headache disorders. The nature of the headache and the associated symptoms during the attack suggest underlying functional alterations in the brain. In this study, we...

    Péter Faragó, Bernadett Tuka, Eszter Tóth, Nikoletta Szabó, András Király, Gergő Csete, Délia Szok, János Tajti, Árpád Párdutz, László Vécsei and Zsigmond Tamás Kincses

    The Journal of Headache and Pain 2017 18:8

    Published on: 25 January 2017

  7. Review article

    The status of diagnosis and treatment to intracranial hypotension, including SIH

    Intracranial hypotension, especially spontaneous intracranial hypotension (SIH), is a well—recognized entity associated with cerebrospinal fluid (CSF) leaks, and has being recognized better in resent years, wh...

    Jin-ping Lin, Shu-dong Zhang, Fei-fang He, Min-jun Liu and Xiao-xu Ma

    The Journal of Headache and Pain 2017 18:4

    Published on: 13 January 2017

  8. Short report

    The relationship between right-to-left shunt and brain white matter lesions in Japanese patients with migraine: a single center study

    There may be a link between right-to-left shunt (RLs) and brain white matter lesions (WMLs) in patients with migraine. In this study, we assessed the relationship between WMLs and RLs in Japanese migraine pati...

    Akio Iwasaki, Keisuke Suzuki, Hidehiro Takekawa, Ryotaro Takashima, Ayano Suzuki, Shiho Suzuki and Koichi Hirata

    The Journal of Headache and Pain 2017 18:3

    Published on: 7 January 2017

  9. Research article

    Excitability of the motor cortex in patients with migraine changes with the time elapsed from the last attack

    Motor-evoked potentials (MEPs) produced by single-pulse transcranial magnetic stimulation (TMS) of the motor cortex can be an objective measure of cortical excitability. Previously, MEP thresholds were found t...

    Francesca Cortese, Gianluca Coppola, Davide Di Lenola, Mariano Serrao, Cherubino Di Lorenzo, Vincenzo Parisi and Francesco Pierelli

    The Journal of Headache and Pain 2017 18:2

    Published on: 6 January 2017

  10. Research article

    Hyperbaric oxygen attenuates neuropathic pain and reverses inflammatory signaling likely via the Kindlin-1/Wnt-10a signaling pathway in the chronic pain injury model in rats

    Hyperbaric oxygen (HBO) therapy is proven to attenuate neuropathic pain in rodents. The goal of the present study was to determine the potential involvement of the Kindlin-1/Wnt-10a signaling pathway during as...

    Baisong Zhao, Yongying Pan, Haiping Xu and Xingrong Song

    The Journal of Headache and Pain 2017 18:1

    Published on: 5 January 2017

  11. Research article

    A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants

    Cluster Headache (CH) is a severe primary headache, with a poorly understood pathophysiology. Complex genetic factors are likely to play a role in CH etiology; however, no confirmed gene associations have been...

    Elena Bacchelli, Maria Michela Cainazzo, Cinzia Cameli, Simona Guerzoni, Angela Martinelli, Michele Zoli, Elena Maestrini and Luigi Alberto Pini

    The Journal of Headache and Pain 2016 17:114

    Published on: 13 December 2016

  12. Research article

    Real-life data in 115 chronic migraine patients treated with Onabotulinumtoxin A during more than one year

    OnabotulinumtoxinA (OnabotA) is effective in Chronic Migraine (CM) during first year of treatment and longer. In real clinical setting, CM patients with acute Medication Overuse (MO) or concurrently receiving ...

    I. Aicua-Rapun, E. Martínez-Velasco, A. Rojo, A. Hernando, M. Ruiz, A. Carreres, E. Porqueres, S. Herrero, F. Iglesias and A. L. Guerrero

    The Journal of Headache and Pain 2016 17:112

    Published on: 12 December 2016

  13. Research article

    Network meta-analysis of migraine disorder treatment by NSAIDs and triptans

    Migraine is a neurological disorder resulting in large socioeconomic burden. This network meta-analysis (NMA) is designed to compare the relative efficacy and tolerability of non-steroidal anti-inflammatory ag...

    Haiyang Xu, Wei Han, Jinghua Wang and Mingxian Li

    The Journal of Headache and Pain 2016 17:113

    Published on: 12 December 2016

  14. Research article

    Headache service quality: evaluation of quality indicators in 14 specialist-care centres

    The study was a collaboration between Lifting The Burden (LTB) and the European Headache Federation (EHF). Its aim was to evaluate the implementation of quality indicators for headache care Europe-wide in special...

    Sara Schramm, Derya Uluduz, Raquel Gil Gouveia, Rigmor Jensen, Aksel Siva, Ugur Uygunoglu, Giorgadze Gvantsa, Maka Mania, Mark Braschinsky, Elena Filatova, Nina Latysheva, Vera Osipova, Kirill Skorobogatykh, Julia Azimova, Andreas Straube, Ozan Emre Eren…

    The Journal of Headache and Pain 2016 17:111

    Published on: 8 December 2016

  15. Research article

    The prevalence of primary headache disorders in Ethiopia

    Knowledge of the epidemiology of primary headache disorders in sub-Saharan Africa (SSA) remains very limited. We performed a population-based survey in rural and urban areas of Ethiopia, using methods similar ...

    Mehila Zebenigus, Redda Tekle-Haimanot, Dawit K. Worku, Hallie Thomas and Timothy J. Steiner

    The Journal of Headache and Pain 2016 17:110

    Published on: 7 December 2016

  16. Research article

    The potential impact of primary headache disorders on stroke risk

    Headache such as migraine is associated with stroke. Studies focused on primary headache disorders (PHDs) as a risk factor for stroke are limited. The purpose of this population-based cohort study was to explo...

    Chia-Lin Tsai, Chung-Hsing Chou, Pei-Jung Lee, Jiu-Haw Yin, Shao-Yuan Chen, Chun-Chieh Lin, Yueh-Feng Sung, Fu-Chi Yang, Chi-Hsiang Chung, Wu-Chien Chien, Chia-Kuang Tsai and Jiunn-Tay Lee

    The Journal of Headache and Pain 2016 17:108

    Published on: 1 December 2016

  17. Research article

    Risk of medication overuse headache across classes of treatments for acute migraine

    The most commonly prescribed medications used to treat migraine acutely are single analgesics, ergots, opioids, and triptans. Due to varying mechanisms of action across drug classes, there is reason to believe...

    Kristian Thorlund, Christina Sun-Edelstein, Eric Druyts, Steve Kanters, Shanil Ebrahim, Rahul Bhambri, Elodie Ramos, Edward J. Mills, Michel Lanteri-Minet and Stewart Tepper

    The Journal of Headache and Pain 2016 17:107

    Published on: 24 November 2016

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