The Journal of Headache and Pain

Official Journal of the "European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"

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Open Access

Cervical muscles in the pathogenesis of migraine headache

The Journal of Headache and PainOfficial Journal of the Italian Society for the Study of Headaches5:62

Received: 22 August 2003

Accepted: 30 October 2003


The pathogenesis of migraine headache is poorly understood but the trigeminovascular system seems to play an important role in it. The trigeminal nucleus caudalis is sensitised by noxious sensory stimuli, often from convergent afferents originating from a variety of tissues. In this paper, we review evidence to support the view that the cervical muscles play a role in the pathogenesis of the migraine headache as well by facilitating the mechanism of central sensitisation.

Key words

Cervical musclesMigraineCentral sensitisationConvergence


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