Open Access

Botulinum toxin type A in the management of headache: a review of the literature and personal experience

The Journal of Headache and PainOfficial Journal of the Italian Society for the Study of Headaches5:63

Received: 1 September 2003

Accepted: 21 November 2003


Botulinum toxin type A (BoNT-A) shows significant promise in the management of a variety of headache types including migraine, chronic daily headache, tension-type headache, and other head and neck pains. Confirmation of efficacy still awaits the report of well-controlled double-blind placebo-controlled trials; however, a mounting body of evidence suggests that BoNT-A is effective, well-tolerated and safe for the management of many headache disorders. In this paper, I review recent evidence on the efficacy of BoNT-A, and also report my personal experience with the treatment in over 600 headache patients.

Key words

Botulinum toxin type ABoNT-AHeadacheChronic daily headacheTension headache