The Journal of Headache and Pain

"European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"

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Open Access

Antiepileptic drugs in migraine prophylaxis

  • Giovanni Mazzotta1Email author,
  • Francesca Floridi1,
  • Andrea Alberti1 and
  • Paola Sarchielli1
The Journal of Headache and PainOfficial Journal of the Italian Society for the Study of Headaches5:111


Research in the field of headache treatment has experienced a marked impetus in the last few years. In the era of the triptans, the treatment modality of this disease has been revolutionised, and though most of the studies conducted have investigated the symptomatic treatment of migraine, less attention has been dedicated to migraine prophylaxis. This review considers the current data available in the literature regarding the use of antiepileptic drugs in migraine prophylaxis, noting the clinical studies that have yielded statistically significant data.

Key words

Migraine prophylaxisAntiepileptics