Open Access

Relapsing–remitting painful ophthalmoplegia due to orbital myositis

  • E. Guaschino1, 2Email author,
  • C. Zandrini1,
  • G. Minonzio1,
  • A. Mancioli1,
  • M. Broggini1 and
  • G. Bono1
The Journal of Headache and Pain20056:254

Published: 15 December 2005


We describe a woman with a long history of relapsing-remitting painful ophthalmoplegia in a seasonal pattern, due to an isolated orbital myositis that was—at our observation–classified in the context of the so-called SAPHO syndrome. She had been previously treated with corticosteroid therapy, but the association with immunosuppressive drugs produced a more prompt resolution of both the headache and ophthalmoplegia, and of the magnetic resonance imaging pictures of isolated myositis as well.

Key words

Painful ophthemolplegiaOrbital myositisSAPHO syndrome