The Journal of Headache and Pain

Official Journal of the "European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"

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Open Access

Spontaneous intracranial hypotension with pituitary adenoma

  • A. K. Firat1Email author,
  • H. M. Karakas1,
  • Z. Y. Firat2,
  • B. Kahraman1 and
  • G. Erdem1
The Journal of Headache and Pain20067:269

Received: 5 December 2005

Accepted: 12 January 2006

Published: 20 February 2006

The Erratum to this article has been published in The Journal of Headache and Pain 2008 9:22


Spontaneous intracranial hypotension (SIH) is an unusual syndrome that is characterised by positional headache, neck rigidity, nausea and vomiting. The characteristic magnetic resonance imaging (MRI) findings are diffuse smooth pachymeningeal thickening and enhancement, downward displacement of posterior fossa structures and pituitary gland enlargement. An unusual case of SIH with pituitary macro–adenoma and subsequent subdural haemorrhage is presented, and its clinical picture, MRI findings and possible pathophysiological mechanism are discussed.

Key words

Spontaneous intracranial hypotensionPituitary adenomaPachymeningeal thickeningSubdural haemorrhage



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