The Journal of Headache and Pain

Official Journal of the "European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"

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Open Access

Spontaneous splenic infarction associated with sumatriptan use

The Journal of Headache and Pain20067:291

Received: 16 April 2006

Accepted: 18 May 2006

Published: 15 June 2006


Triptans are specific agonists of the serotonergic 5-HT1B/1D receptors that have increasingly been used in the treatment of migraine and cluster headaches. Though they are generally considered safe, there have been a few reports of myocardial infarction and stroke associated with triptan use. We report a patient who developed spontaneous splenic infarction after the use of sumatriptan for the treatment of migraine headache.

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