The Journal of Headache and Pain

"European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"

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Open Access

TNFA gene: the -308 promoter polymorphism in migraine

  • Monica Poscente,
  • Gloria Brioli,
  • Patrizia Lulli,
  • Marina Morellini,
  • Paolo Martelletti,
  • Mario Giacovazzo and
  • Simonetta Trabace
The Journal of Headache and PainOfficial Journal of the Italian Society for the Study of Headaches1:0001S169.10194


Molecular analysis of TNFA alleles in Italian subjects affected by migraine was performed in order to define the involfement of HLA region genes in migraine. No statistically significant differences in TNFA allele distribution between patients and controls were observed.

Key words HLATNFMigraineSusceptibility