The Journal of Headache and Pain

Official Journal of the "European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"

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Volume 15 Supplement 1

Abstracts from the 4th European Headache and Migraine Trust International Congress: EHMTIC 2014

Open Access

EHMTI-0203. Increased prevalence of migraine without aura in patients with saccular intracranial aneurysms (SIA) and remission after clipping of the aneurysm

  • ER Lebedeva1,
  • AV Busygina1,
  • EY Guzhina2,
  • VS Kolotvinov3,
  • VP Sakovich2 and
  • J Olesen4
The Journal of Headache and Pain201415(Suppl 1):D36

Published: 18 September 2014


Public HealthInternal MedicineMigraineBlood DonorPast History


The aim of our study was to determine 1-year prevalence of headache before rupture of saccular intracranial aneurysms (SIA) and 1-year after clipping of SIA.


We prospectively studied 199 consecutive patients with SIA (103 females and 96 males, mean age: 43.2 years).As control served 194 blood donors (86 females, 108 males, mean age: 38.4 years). Both groups were interviewed about headaches in the year preceding clipping/interview using a validated semi-structured neurologist conducted interview. SIA patients with a past history of recurrent headaches (N=87) were follow-up 1 year after clipping. The remission rates of migraine and tension-type headache (TTH) in these patients was compared to 92 patients from a headache center interviewed twice one year apart. Diagnoses were made according to the ICHD-2.


During the year before rupture, 124(62.3%) had one or more types of headache: migraine without aura (MO) -78(39.2%), migraine with aura - 2(1%), probable migraine: 4(2%), TTH: 39(19.6%), cluster headache: 2(1%).Only the prevalence of MO was significantly higher in patients with SIA compare to controls (39.2% VS 8.8%, OR 6.7, 95% CI 3.8-11.9, p<0.0001).One year after clipping, the prevalence of MO was significantly more reduced in patients with SIA than in controls (74.5% VS 12.8%, p<0.0001).No factors except clipping of the aneurysm could explain the remission of migraine. The prevalence of TTH did not change significantly after clipping of SIA but decreased significantly after treatment in controls.


Unruptured SIA is associated with a marked increase in the prevalence of migraine without aura which decreases significantly after clipping.

No conflict of interest.

Authors’ Affiliations

Neurology, the Urals state medical university International Headache Center "Europe-Asia", Yekaterinburg, Russia
Neurology and Neurosurgery, the Urals state medical university, Yekaterinburg, Russia
Neurosurgery, City Hospital 40 Regional neurosurgical center, Yekaterinburg, Russia
Neurology, Glostrup Hospital University of Copenhagen, Copenhagen, Denmark


© Lebedeva et al; licensee Springer. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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