The Journal of Headache and Pain

Official Journal of the "European Headache Federation" and of "Lifting The Burden - The Global Campaign against Headache"

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Volume 15 Supplement 1

Abstracts from the 4th European Headache and Migraine Trust International Congress: EHMTIC 2014

Open Access

EHMTI-0107. Treatment of migraine in Croatia, year 2013

  • V Vukovic Cvetkovic1,
  • S Zupanic2 and
  • M Podgornik3
The Journal of Headache and Pain201415(Suppl 1):G41

Published: 18 September 2014


MagnesiumMigraineInternet SitePublic Health ProblemHealth Study


To estimate the burden and current treatment patterns of migraine in Croatia.


This was a public health study conducted from April to June 2013. in Croatia. A questionnaire with 10 questiones was sent to 2750 E-mail addresses, randomly chosen from various internet sites.


Of 2750 sent E mails, 246 declared having migraine; 209 (85 %) were women (56.5% aged 18-45 years; 28.7 % aged 46-65 year; 37 (15 %) were men (8.1 % aged 18-45 years and 6.5 % aged 46-65 years). Up to 2 attacks per month had 59.4 %, 2-10 attacks had 38.6% and > 10 attacks had 2% of respondents. In the last 3 months, 74.4% was never absent from work because of headache, 20.7% was absent < 2 days and 4.9% was absent >3 days. Working with 50% reduced capacity declared 21.5% on < 2 days, 24% on 3-4 days and 21.6 % on > 5 days. In acute migraine attacks 71.5% used NSAIDs and simple analgesics, 9.4% triptans, 11.4% combination of drugs (NSAIDs+triptan) and 3.3% ergotamins. Two drugs per attack takes 39.4%, one drug 26.4% and >3 drugs 30.9%. Only 9.4% respondents was completely satisfied with acute drug treatment, 75% efficacy declared 33.7%, 50% efficacy 32.1% and less than 25% efficacy declared 23.6%. Prophylactic therapy (beta blockers, antidepressants or anticonvulsives) used 7.3%; 11% used magnesium, vitamins or herbal drugs.


This study provides the most current available estimates of the impact and treatment patterns of migraine in Croatia. Migraine is under-treated and represents a major public health problem.

No conflict of interest.

Authors’ Affiliations

Department of Neurology, Univesity Hospital Center "Sestre Milosrdnice", Zagreb, Croatia
General Practice "Krunoslav Reljanovic", General Practice "Krunoslav Reljanovic", Zagreb, Croatia
University School of medicine Zagreb, University School of Medicine Zagreb, Zagreb, Croatia


© Cvetkovic et al; licensee Springer. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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